Contini, Alessandro E.Flood, NathanMcAteer, DanielMai, NathalieAkhavan, Jacqueline2020-01-092020-01-092015-10-06Contini AE, Flood N, McAteer D, et al., (2015) Low hazard small-scale synthesis and chemical analysis of high purity nitroglycerine (NG). RSC Advances, Volume 5, Issue 106, 2015, pp. 87228-872322046-2069https:/doi.org/10.1039/C5RA17951Chttp://dspace.lib.cranfield.ac.uk/handle/1826/14903A previously reported two-phase (99.5% fuming nitric acid/dichloromethane) batch method to prepare high purity 1,2,3-propanetriyl trinitrate (nitroglycerine, NG) was evaluated, simplified and adapted specifically for low hazard small-scale synthesis. The purity of the product, as determined by NMR spectroscopy, HPLC and IR spectroscopic analysis was found to be greater than 99%. The quick synthetic method is highly recommended when small amounts of highly pure NG are required for analytical and related purposes in the absence of a microreactor.enAttribution-NonCommercial 4.0 Internationalhttp://creativecommons.org/licenses/by-nc/4.0/Article1916629