Kumar, VinodPark, Sunghoon2017-12-182017-12-182017-10-19Vinod Kumar, Sunghoon Park, Potential and limitations of Klebsiella pneumoniae as a microbial cell factory utilizing glycerol as the carbon source, Biotechnology Advances, Volume 36, Issue 1, January–February 2018, Pages 150-1670734-9750https://doi.org/10.1016/j.biotechadv.2017.10.004http://dspace.lib.cranfield.ac.uk/handle/1826/12771Klebsiella pneumoniae is a Gram-negative facultative anaerobe that metabolizes glycerol efficiently under both aerobic and anaerobic conditions. This microbe is considered an outstanding biocatalyst for transforming glycerol into a variety of value-added products. Crude glycerol is a cheap carbon source and can be converted by K. pneumoniae into useful compounds such as lactic acid, 3-hydroxypropionic acid, ethanol, 1,3-propanediol, 2,3-butanediol, and succinic acid. This review summarizes glycerol metabolism in K. pneumoniae and its potential as a microbial cell factory for the production of commercially important acids and alcohols. Although many challenges remain, K. pneumoniae is a promising workhorse when glycerol is used as the carbon source.enAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/Klebsiella pneumoniaeGlycerol3-Hydroxypropionic acid1,3-Propanediol2,3-ButanediolLactic acidEthanolArticle