Larcombe, Lee DClark, TaaneBessant, ConradGoulden, Matthew G2024-03-132024-03-132012-03https://dspace.lib.cranfield.ac.uk/handle/1826/20976NGS sequencing libraries prepared on an Illumina NGS platform for 10 isolates of Staphylococcus aureus were analysed. After extensive pre-processing to address library quality issues, for each isolate the status of the Staphylococcal Chromosome Cassette, and its mecA gene specifying resistance to meticillin, was determined. All mecA-positive isolates encoded canonical mecA. None encoded the new variant mecA identified in strain LGA251.encore genomeaccessory genomeNGS sequencing librariesdrug resistanceAnalysis of MRSA Staphylococcal Chromosome cassette mecA status from next generation sequence dataThesis or dissertation