Woodman, Anthony C.Larcombe, L.2017-01-182017-01-182006-02http://dspace.lib.cranfield.ac.uk/handle/1826/11297This work set out to apply computational tools and biophysics principles to develop a systematic approach to the rational selection of synthetic antigens from appropriate DNA sequences. The wider potential to the rapid development of diagnostics will be demonstrated by application towards a chlamydia-specific immunodiagnostic, and the potential for vaccine and therapeutic development will be discussed.en© Cranfield University, 2006. All rights reserved. No part of this publication may be reproduced without the written permission of the copyright holder.Thesis or dissertation