Sun, XiuchaoDuan, MengluLi, RongtengMeng, YuanBai, QiangWang, LinaLiu, ManhongYang, ZhugenZhu, ZhilingSui, Ning2022-10-052022-10-052022-09-19Sun X, Duan M, Li R, et al., (2022) Ultrathin graphdiyne/graphene heterostructure as a robust electrochemical sensing platform. Analytical Chemistry, Volume 94, Issue 39, September 2022, pp. 13598-136060003-2700https://doi.org/10.1021/acs.analchem.2c03387https://dspace.lib.cranfield.ac.uk/handle/1826/18516Graphdiyne (GDY) has been considered as an appealing electrode material for electrochemical sensing because of its alkyne-rich structure and high degrees of π-conjugation, which shows great affinity to heavy metal ions and pollutant molecules via d−π and π–π interactions. However, the low surface area and poor conductivity of bulk GDY limit its electrochemical performance. Herein, a two-dimensional ultrathin GDY/graphene (GDY/G) nanostructure was synthesized and used as an electrode material for electrochemical sensing. Graphene plays the role of an epitaxy template for few-layered GDY growth and conductive layers. The formed few-layered GDY with a high surface area possesses abundant affinity sites toward heavy metal ions (Cd2+, Pb2+) and toxic molecules, for example, nitrobenzene and 4-nitrophenol, via d−π and π–π interactions, respectively. Moreover, hemin as a key part of the enzyme catalytic motif was immobilized on GDY/G via π–π interactions. The artificial enzyme mimic hemin/GDY/G-modified electrode exhibited promising ascorbic acid and uric acid detection performance with excellent sensitivity and selectivity, a good linear range, and reproducibility. More importantly, real sample detection and the feasibility of this electrochemical sensor as a wearable biosensor were demonstrated.enAttribution-NonCommercial 4.0 Internationalhttp://creativecommons.org/licenses/by-nc/4.0/Article