Potential and limitations of Klebsiella pneumoniae as a microbial cell factory utilizing glycerol as the carbon source
dc.contributor.author | Kumar, Vinod | |
dc.contributor.author | Park, Sunghoon | |
dc.date.accessioned | 2017-12-18T11:31:47Z | |
dc.date.available | 2017-12-18T11:31:47Z | |
dc.date.issued | 2017-10-19 | |
dc.description.abstract | Klebsiella pneumoniae is a Gram-negative facultative anaerobe that metabolizes glycerol efficiently under both aerobic and anaerobic conditions. This microbe is considered an outstanding biocatalyst for transforming glycerol into a variety of value-added products. Crude glycerol is a cheap carbon source and can be converted by K. pneumoniae into useful compounds such as lactic acid, 3-hydroxypropionic acid, ethanol, 1,3-propanediol, 2,3-butanediol, and succinic acid. This review summarizes glycerol metabolism in K. pneumoniae and its potential as a microbial cell factory for the production of commercially important acids and alcohols. Although many challenges remain, K. pneumoniae is a promising workhorse when glycerol is used as the carbon source. | en_UK |
dc.identifier.citation | Vinod Kumar, Sunghoon Park, Potential and limitations of Klebsiella pneumoniae as a microbial cell factory utilizing glycerol as the carbon source, Biotechnology Advances, Volume 36, Issue 1, January–February 2018, Pages 150-167 | en_UK |
dc.identifier.issn | 0734-9750 | |
dc.identifier.uri | https://doi.org/10.1016/j.biotechadv.2017.10.004 | |
dc.identifier.uri | http://dspace.lib.cranfield.ac.uk/handle/1826/12771 | |
dc.language.iso | en | en_UK |
dc.publisher | Elsevier | en_UK |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 International | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Klebsiella pneumoniae | en_UK |
dc.subject | Glycerol | en_UK |
dc.subject | 3-Hydroxypropionic acid | en_UK |
dc.subject | 1,3-Propanediol | en_UK |
dc.subject | 2,3-Butanediol | en_UK |
dc.subject | Lactic acid | en_UK |
dc.subject | Ethanol | en_UK |
dc.title | Potential and limitations of Klebsiella pneumoniae as a microbial cell factory utilizing glycerol as the carbon source | en_UK |
dc.type | Article | en_UK |
Files
Original bundle
1 - 1 of 1
Loading...
- Name:
- Potential_and_Limitations_of_Klebsiella pneumoniae-2017.pdf
- Size:
- 2.27 MB
- Format:
- Adobe Portable Document Format
- Description:
License bundle
1 - 1 of 1
No Thumbnail Available
- Name:
- license.txt
- Size:
- 1.63 KB
- Format:
- Item-specific license agreed upon to submission
- Description: