Potential and limitations of Klebsiella pneumoniae as a microbial cell factory utilizing glycerol as the carbon source

dc.contributor.authorKumar, Vinod
dc.contributor.authorPark, Sunghoon
dc.date.accessioned2017-12-18T11:31:47Z
dc.date.available2017-12-18T11:31:47Z
dc.date.issued2017-10-19
dc.description.abstractKlebsiella pneumoniae is a Gram-negative facultative anaerobe that metabolizes glycerol efficiently under both aerobic and anaerobic conditions. This microbe is considered an outstanding biocatalyst for transforming glycerol into a variety of value-added products. Crude glycerol is a cheap carbon source and can be converted by K. pneumoniae into useful compounds such as lactic acid, 3-hydroxypropionic acid, ethanol, 1,3-propanediol, 2,3-butanediol, and succinic acid. This review summarizes glycerol metabolism in K. pneumoniae and its potential as a microbial cell factory for the production of commercially important acids and alcohols. Although many challenges remain, K. pneumoniae is a promising workhorse when glycerol is used as the carbon source.en_UK
dc.identifier.citationVinod Kumar, Sunghoon Park, Potential and limitations of Klebsiella pneumoniae as a microbial cell factory utilizing glycerol as the carbon source, Biotechnology Advances, Volume 36, Issue 1, January–February 2018, Pages 150-167en_UK
dc.identifier.issn0734-9750
dc.identifier.urihttps://doi.org/10.1016/j.biotechadv.2017.10.004
dc.identifier.urihttp://dspace.lib.cranfield.ac.uk/handle/1826/12771
dc.language.isoenen_UK
dc.publisherElsevieren_UK
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectKlebsiella pneumoniaeen_UK
dc.subjectGlycerolen_UK
dc.subject3-Hydroxypropionic aciden_UK
dc.subject1,3-Propanediolen_UK
dc.subject2,3-Butanediolen_UK
dc.subjectLactic aciden_UK
dc.subjectEthanolen_UK
dc.titlePotential and limitations of Klebsiella pneumoniae as a microbial cell factory utilizing glycerol as the carbon sourceen_UK
dc.typeArticleen_UK

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