2D spatially-resolved depth-section microfluidic flow velocimetry using dual beam OCT

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dc.contributor.authorHallam, Jonathan M.
dc.contributor.authorRigas, Evangelos
dc.contributor.authorCharrett, Thomas O. H.
dc.contributor.authorTatam, Ralph P.
dc.date.accessioned2020-04-09T15:14:31Z
dc.date.available2020-04-09T15:14:31Z
dc.date.freetoread2020-04-09
dc.date.issued2020-03-27
dc.description.abstractA dual beam optical coherence tomography (OCT) instrument has been developed for flow measurement that offers advantages over microscope derived imaging techniques. It requires only a single optical access port, allows simultaneous imaging of the microfluidic channel, does not require fluorescent seed particles, and can provide a millimetre-deep depth-section velocity profile (as opposed to horizontal-section). The dual beam instrument performs rapid re-sampling of particle positions, allowing measurement of faster flows. In this paper, we develop the methods and processes necessary to make 2D quantitative measurements of the flow-velocity using dual beam OCT and present exemplar results in a microfluidic chip. A 2D reference measurement of the Poiseuille flow in a microfluidic channel is presented over a spanwise depth range of 700 μm and streamwise length of 1600 μm with a spatial resolution of 10 μm, at velocities up to 50 mm/s. A measurement of a more complex flow field is also demonstrated in a sloped microfluidic section.en_UK
dc.identifier.citationHallam JM, Rigas E, Charrett TO, Tatam RP. (2020) 2D spatially-resolved depth-section microfluidic flow velocimetry using dual beam OCT. Micromachines, Volume 11, Issue 4, March 2020, Article number 351en_UK
dc.identifier.cris26703844
dc.identifier.issn2072-666X
dc.identifier.urihttps://doi.org/10.3390/mi11040351
dc.identifier.urihttps://dspace.lib.cranfield.ac.uk/handle/1826/15391
dc.language.isoenen_UK
dc.publisherMDPIen_UK
dc.rightsAttribution 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectparticle image velocimetry (PIV)en_UK
dc.subjectflow measurementen_UK
dc.subjectmicrofluidicsen_UK
dc.subjectinterferometryen_UK
dc.subjectoptical coherence tomography (OCT)en_UK
dc.title2D spatially-resolved depth-section microfluidic flow velocimetry using dual beam OCTen_UK
dc.typeArticleen_UK

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