Gaussian Bayesian network comparisons with graph ordering unknown

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dc.contributor.authorZhang, Hongmei
dc.contributor.authorHuang, Xianzheng
dc.contributor.authorHan, Shengtong
dc.contributor.authorRezwan, Faisal I.
dc.contributor.authorKarmaus, Wilfried
dc.contributor.authorArshad, Syed Hasan
dc.contributor.authorHolloway, John W.
dc.date.accessioned2021-02-24T11:23:52Z
dc.date.available2021-02-24T11:23:52Z
dc.date.issued2020-12-26
dc.description.abstractA Bayesian approach is proposed that unifies Gaussian Bayesian network constructions and comparisons between two networks (identical or differential) for data with graph ordering unknown. When sampling graph ordering, to escape from local maximums, an adjusted single queue equi-energy algorithm is applied. The conditional posterior probability mass function for network differentiation is derived and its asymptotic proposition is theoretically assessed. Simulations are used to demonstrate the approach and compare with existing methods. Based on epigenetic data at a set of DNA methylation sites (CpG sites), the proposed approach is further examined on its ability to detect network differentiations. Findings from theoretical assessment, simulations, and real data applications support the efficacy and efficiency of the proposed method for network comparisons.en_UK
dc.identifier.citationZhang H, Huang X, Han S, et al., (2021) Gaussian Bayesian network comparisons with graph ordering unknown. Computational Statistics and Data Analysis, Volume 157, May 2021, Article number 107156en_UK
dc.identifier.issn0167-9473
dc.identifier.urihttps://doi.org/10.1016/j.csda.2020.107156
dc.identifier.urihttp://dspace.lib.cranfield.ac.uk/handle/1826/16397
dc.language.isoenen_UK
dc.publisherElsevieren_UK
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectBayesian methodsen_UK
dc.subjectDNA methylationen_UK
dc.subjectSingle Queue Equi-Energyen_UK
dc.subjectDifferential Gaussian Bayesian networken_UK
dc.subjectVariable selectionsen_UK
dc.subjectOrderingen_UK
dc.titleGaussian Bayesian network comparisons with graph ordering unknownen_UK
dc.typeArticleen_UK

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