Monitoring occurrence of SARS-CoV-2 in school populations: a wastewater-based approach

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dc.contributor.authorCastro-Gutierrez, Victor
dc.contributor.authorHassard, Francis
dc.contributor.authorVu, Milan
dc.contributor.authorLeitao, Rodrigo
dc.contributor.authorBurczynska, Beata
dc.contributor.authorWildeboer, Dirk
dc.contributor.authorStanton, Isobel
dc.contributor.authorRahimzadeh, Shadi
dc.contributor.authorBaio, Gianluca
dc.contributor.authorGarelick, Hemda
dc.contributor.authorHofman, Jan
dc.contributor.authorKasprzyk-Hordern, Barbara
dc.contributor.authorKwiatkowska, Rachel
dc.contributor.authorMajeed, Azeem
dc.contributor.authorPriest, Sally
dc.contributor.authorGrimsley, Jasmine
dc.contributor.authorLundy, Lian
dc.contributor.authorSinger, Andrew C.
dc.contributor.authorDi Cesare, Mariachiara
dc.date.accessioned2022-07-19T15:14:05Z
dc.date.available2022-07-19T15:14:05Z
dc.date.issued2022-06-17
dc.description.abstractClinical testing of children in schools is challenging, with economic implications limiting its frequent use as a monitoring tool of the risks assumed by children and staff during the COVID-19 pandemic. Here, a wastewater-based epidemiology approach has been used to monitor 16 schools (10 primary, 5 secondary and 1 post-16 and further education) in England. A total of 296 samples over 9 weeks have been analysed for N1 and E genes using qPCR methods. Of the samples returned, 47.3% were positive for one or both genes with a detection frequency in line with the respective local community. WBE offers a low cost, non-invasive approach for supplementing clinical testing and can provide longitudinal insights that are impractical with traditional clinical testing.en_UK
dc.identifier.citationCastro-Gutierrez V, Hassard F, Vu M, et al., (2022) Monitoring occurrence of SARS-CoV-2 in school populations: a wastewater-based approach, PLoS ONE, Volume 17, Issue 6, June 2022, Article number e0270168en_UK
dc.identifier.issn1932-6203
dc.identifier.urihttps://doi.org/10.1371/journal.pone.0270168
dc.identifier.urihttps://dspace.lib.cranfield.ac.uk/handle/1826/18193
dc.language.isoenen_UK
dc.publisherPLOS (Public Library of Science)en_UK
dc.rightsAttribution 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.titleMonitoring occurrence of SARS-CoV-2 in school populations: a wastewater-based approachen_UK
dc.typeArticleen_UK

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