Introducing MINA-The Molecularly Imprinted Nanoparticles Assay

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Shutov, Roman V.
Guerreiro, Antonio R.
Moczko, Ewa
Perez De Vargas Sansalvador, Isabel M.
Chianella, Iva
Whitcombe, Michael J.
Piletsky, Sergey A.

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1613-6810

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Shutov RV, Guerreiro A, Moczko E, et al., (2014) Introducing MINA - The Molecularly Imprinted Nanoparticles Assay. Small, Volume 10, Issue 6, March 2014, pp. 1086-1089

Abstract

A new ELISA‐ (enzyme‐linked immunosorbent assay)‐like assay is demonstrated in which no elements of biological origin are used for molecular recognition or signaling. Composite imprinted nanoparticles that contain a catalytic core and which are synthesized by using a solid‐phase approach can simultaneously act as recognition/signaling elements, and be used with minimal modifications to standard assay protocols. This assay provides a new route towards replacement of unstable biomolecules in immunoassays.

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Attribution-NonCommercial 4.0 International

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