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Optical assay for biotechnology and clinical diagnosis

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0018-9294

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Moczko E, Cauchi M, Turner C, et al., (2011) Optical assay for biotechnology and clinical diagnosis. IEEE Transactions on Biomedical Engineering, Volume 58, Issue 8, August 2011, pp. 2154-2160

Abstract

In this paper, we present an optical diagnostic assay consisting of a mixture of environmental-sensitive fluorescent dyes combined with multivariate data analysis for quantitative and qualitative examination of biological and clinical samples. The performance of the assay is based on the analysis of spectrum of the selected fluorescent dyes with the operational principle similar to electronic nose and electronic tongue systems. This approach has been successfully applied for monitoring of growing cell cultures and identification of gastrointestinal diseases in humans.

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© 2011 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other users, including reprinting/ republishing this material for advertising or promotional purposes, creating new collective works for resale or redistribution to servers or lists, or reuse of any copyrighted components of this work in other works.

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